Development of a safe neutralization assay for SARS-CoV and characterization of S-glycoprotein
β Scribed by Dong P Han; Hyung G Kim; Young B Kim; Leo L.M Poon; Michael W Cho
- Book ID
- 113945987
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 572 KB
- Volume
- 326
- Category
- Article
- ISSN
- 0042-6822
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## Abstract A high throughput accurate assay for antiβSARSβCoV IgG detection is needed for largeβscale epidemiological studies. The evaluation of a commercial recombinant nucleocapsid proteinβbased microtitre plate enzyme immunoassay, ELISARSβ’ is described. The results on 150 sera from SARS patient
Severe acute respiratory syndrome (SARS)-coronavirus (SARS-CoV) is the causative agent of SARS. The S protein of SARS-CoV is a major target for neutralizing antibodies (Nabs) in infected patients. We developed a neutralization assay using a recombinant vesicular stomatitis virus (VSV) bearing SARS-C