𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Development of a Practical and Scalable Synthesis of a Potent Selective Dual Antagonist for 5-HT2B and 5-HT7 Receptors

✍ Scribed by Yoshida, Shinya; Kasai, Makoto; Kimura, Takenori; Akiba, Takahiro; Takahashi, Takumi; Sakamoto, Shuichi


Book ID
120430790
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
715 KB
Volume
16
Category
Article
ISSN
1083-6160

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Rapid synthesis of [18F]SR46349B, a pote
✍ Pingzhong Tan; Joanna S. Fowler; Yu-Shin Ding; David J. Schlyer πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 483 KB

## Abstract F‐18 labeled SR46349B, a highly potent and selective 5‐HT~2~ receptor antagonist, was synthesized as a potential radioligand for PET studies of brain 5‐HT~2~ receptors. Nucleophilic aromatic substitution of __trans__‐1‐(2‐nitrophenyl)‐3‐(4‐methoxymethoxyphenyl)‐2‐propenone (10) with NCA