𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Development of a physiologically based model for the toxicokinetics of C(±)P(±)-soman in the atropinized guinea pig

✍ Scribed by Jan P. Langenberg; C. Van Dijk; Richard E. Sweeney; Donald M. Maxwell; Leo P. A. De Jong; Hendrik P. Benschop


Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
242 KB
Volume
71
Category
Article
ISSN
0340-5761

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Changes in guinea pig plasma cyclic nucl
✍ P. J. Wood; G. Pao; A. Cooper 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB 👁 2 views

Plasma levels of cyclic AMP and cyclic GMP were determined in 35 guinea pigs for up to 9 days following subcutaneous passage of L2C leukemia cells. Twenty guinea pigs into which normal syngeneic guinea pig thymocytes were passaged served as controls. Cyclic AMP levels in plasma showed little change

Physiologically based pharmacokinetic mo
✍ Frans G. M. Russel; Alfons C. Wouterse; Cees A. M. Van Ginneken 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 704 KB

Plasma kinetics and renal excretion of iodopyracet (3\*0g, adminstered i.v.) with and without concomitant administration of probenecid were studied in the beagle dog. Pharmacokinetic analysis revealed that tubular secretion is the predominant route of excretion, and that secretion is inhibited by pr

A physiologically based kidney model for
✍ Sandra P. A. Boom; Ineke Meyer; Alfons C. Wouterse; Frans G. M. Russel 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB 👁 2 views

Ranitidine renal clearance was investigated in the beagle dog with or without concomitant infusion of cimetidine or probenecid. Ranitidine was excreted mainly by renal tubular secretion. Plasma clearance was reduced by probenecid from 198 9 47 to 119 9 41 mL min -1 (mean9 S.D.); renal clearance was