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Development of a novel three-dimensional culture system to study the role of mechanically damaged osteocytes in the initiation of targeted bone remodeling

✍ Scribed by Heino, T.J.; Kurata, K.; Higaki, H.; Väänänen, H.K.


Book ID
108333803
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
154 KB
Volume
39
Category
Article
ISSN
0021-9290

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Role of mechanically damaged osteocytes
✍ Kosaku Kurata; Takanobu Fukunaga; Junpei Matsuda; Hidehiko Higaki 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 476 KB

Microdamage is naturally contained in bone and has been considered to trigger bone remodeling. Osteocytes, which exist in bone matrix forming 3-D cell-to-cell network, provide cellular basis to detect local mechanical environment neighboring the microdamage, and should be involved in the initiating