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Development of a Novel Method for Warfarin Synthesis via Lipase-Catalyzed Steroselective Michael Reaction

โœ Scribed by Uwai, Koji; Sano, Kaoru; Saito, Shun-ichi; Hirose, Yoshihiko; Kohari, Yoshihito; Nakano, Hiroto; Seki, Chigusa; Tokiwa, Michio; Takeshita, Mitsuhiro


Book ID
120326462
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2013
Tongue
English
Weight
450 KB
Volume
87
Category
Article
ISSN
0385-5414

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The Mitsunobu reaction: A novel method f
โœ Michael A. Walker ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 276 KB

Compounds l-7 were synthesized from maleimicfe and the corresponding alcohols using a novel application of the Mitsunobu reaction. This procedure allows the direct formation of a variety of bifunctional linker compounds. Bifunctional linkers, with a maleimido group attached to one end and a connecta