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Development of a novel 19F MRI probe for detecting amyloid deposition in Alzheimer's disease

โœ Scribed by Daijiro Yanagisawa; Shigehiro Morikawa; Hiroyasu Taguchi; Akihiko Shiino; Toshiro Inubushi; Ikuo Tooyama


Book ID
116778747
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
56 KB
Volume
71
Category
Article
ISSN
0168-0102

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Passive staining: A novel ex vivo MRI pr
โœ Marc Dhenain; Benoรฎt Delatour; Christine Walczak; Andreas Volk ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 470 KB

## Abstract Amyloid plaques are one of the hallmarks of Alzheimer's disease (AD). This study evaluated a novel ฮผMRI strategy based on โ€œpassive stainingโ€ of brain samples by gadoteric acid. The protocol was tested at 4.7T on control animals and APP/PS1 mice modeling AD lesions. T~1~ was strongly dec