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Development of a New RAM-Chiral Column for Determination of Chiral Drugs in Biological Fluids by HPLC

✍ Scribed by G. Félix; D. Campèse

Book ID
111790813
Publisher
Springer
Year
2007
Tongue
English
Weight
394 KB
Volume
66
Category
Article
ISSN
0009-5893

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A simple and sensitive HPLC method was developed and validated for the determination of four frequently prescribed 1,4-benzodiazepines: alprazolam (ALP), bromazepam (BRZ), diazepam (DZP), and flunitrazepam (FNZ). Separation was achieved on an Inertsil C8 analytical (250 mm x 4 mm, 5 microm) column,