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Development of a new acyl anion equivalent for the preparation of masked activated esters, and their use to prepare a dipeptide

✍ Scribed by Nemoto, Hisao; Kubota, Yasufumi; Yamamoto, Yoshinori


Book ID
120004748
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
290 KB
Volume
55
Category
Article
ISSN
0022-3263

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A method for the preparation of a-azido-masked acyl cyanides as synthetic equivalents of N-protected-C-activated a-amino acids was developed using carbon-carbon bond formation between aldehydes and the Masked Acyl Cyanide Reagents, followed by sulfonylation and substitution by azide anion. This meth