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Development of a multidose formulation for a humanized monoclonal antibody using experimental design techniques

โœ Scribed by Gupta, Supriya ;Kaisheva, Elizabet


Book ID
111766939
Publisher
Springer US
Year
2003
Tongue
English
Weight
122 KB
Volume
5
Category
Article
ISSN
1530-9932

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Aggregation is a critical issue that hampers the development of monoclonal antibody therapeutics (Mabs). Traditionally, aggregation is considered a process in which native forms of proteins are transformed into an unstable highly associated form through an intermediate formation step. Here we descri