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Development of a multicomponent candidate vaccine for HIV-1

✍ Scribed by Jong J. Kim; Velpandi Ayyavoo; Mark L. Bagarazzi; Michael Chattergoon; Jean D. Boyer; Bin Wang; David B. Weiner


Book ID
117432431
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
696 KB
Volume
15
Category
Article
ISSN
0264-410X

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## Abstract A thirty amino acid synthetic peptide (HGP30) representing the conserved region of HIV‐1 p17 induced high titer antibodies to the native pl7 in rabbits. This immune sera neutralized HIV‐1 replication in cell culture and one of the high titer antisera also inhibited CD4‐dependent cell fu