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Development of a multi-step approach for the detection of neutralising antibodies to botulinum toxin Type A

✍ Scribed by Pickett Andy; Morte Carles; Pla Francesc; Cedo Mar; Mirabet Maribel; Peraire Concepcion; Obach Rosendo; O’Keeffe Roderic

Book ID
116922073
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
38 KB
Volume
51
Category
Article
ISSN
0041-0101

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✍ Kirn R. Kessler; Dr. Reiner Benecke 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 427 KB

## Abstract Approximately 5 to 10% of patients with cervical, segmental or multifocal dystonia receiving repetitive local injections with botulinum toxin A (BTX A) are estimated to develop secondary loss of treatment benefit (nonresponding) because of the formation of circulating serum antibodies a