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Development of a monoclonal antibody specific for human bone alkaline phosphatase

โœ Scribed by Masuhara, K.; Suzuki, S.; Yoshikawa, H.; Tsuda, T.; Takaoka, K.; Ono, K.; Morris, David C.; Hsu, Howard H.; Anderson, H. Clarke

Book ID
122971359
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
364 KB
Volume
17
Category
Article
ISSN
0169-6009

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๐Ÿ“œ SIMILAR VOLUMES

Monoclonal antibody against human bone a
Monoclonal antibody against human bone alkaline phosphatase
โœ K. Masuhara; R. Yoshikawa; K. Takaoka; K. Ono; D. C. Morris; H. C. Anderson ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 318 KB

A monoclonal antibody which reacts preferentially with human bone alkaline phosphatase (AP) has been developed using human osteosarcoma bone AP as an immunogen. The antibody with the highest selectivity shows about three- and a-half fold greater binding to bone than to liver AP. The selectivity was