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Development of a model that contains both multipole moments and gaussians for the calculation of molecular electrostatic potentials

✍ Scribed by James R. Rabinowitz; Stephen B. Little


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
771 KB
Volume
34
Category
Article
ISSN
0020-7608

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Gene-directed enzyme prodrug therapy for
✍ Rosetta Martiniello-Wilks; Allison Dane; Dale J. Voeks; Geetha Jeyakumar; Elin M πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 310 KB πŸ‘ 1 views

## Abstract ## Background Gene‐directed enzyme prodrug therapy (GDEPT) based on the __E. coli__ enzyme purine nucleoside phosphorylase (PNP) represents a new approach for treating slow growing tumours like prostate cancer (PCa). Expressed enzyme converts a systemically administered prodrug, fludar