Development of a laser plasma x-ray microscope to observe live hydrated biological specimens

✍ Scribed by M. Kado; H. Daido; Y. Yamamoto; K. Shinohara; M. C. Richardson

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 99 KB
• Volume: 3
• Category: Article
• ISSN: 1612-2011
• DOI: 10.1002/lapl.200510074

✦ Synopsis

Investigating the structure and the function of life
object performing advanced life activity becomes important. In
order to investigate the life object, it is necessary to observe
living specimens with high spatial resolution and high temporal
resolution. Since laser plasma x-ray source has high brightness
and short pulse duration, x-ray microscope with the laser plasma
x-ray source makes possible to observe living specimens. Such as
chromosomes, macrophages, bacterium, and so on have been observed
by contact x-ray microscopy. The x-ray images obtained by indirect
measurements such as the contact x-ray microscopy have difficulty
to avoid artificial effect such as irregular due to developing
process. Development of an x-ray microscope with laser plasma
x-ray source is necessary to avoid such defects. We have been
developing an x-ray microscope with laser plasma x-ray source to
observe wet live specimens. The detail of the x-ray microscope
will be presented.