Development of a Fluorescence Resonance Energy Transfer Peptide Library Technology for Detection of Protease Contaminants in Protein-Based Raw Materials Used in Diagnostic Assays

Development of a Homogeneous, Fluorescen

Development of a Homogeneous, Fluorescence Resonance Energy Transfer-Based in Vitro Recruitment Assay for Peroxisome Proliferator-Activated Receptor δ via Selection of Active LXXLL Coactivator Peptides

✍ Katherine A. Drake; Ji-Hu Zhang; Richard K. Harrison; Gerald M. McGeehan 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 88 KB

The peroxisome proliferator-activated receptors (PPARs) are nuclear receptors activated by fatty acids and their metabolites. The PPAR␦ subtype is believed to be involved in lipoprotein regulation and may have a role in reverse cholesterol transport. While the range of biological roles of PPAR␦ stil