Development of a chronic toxicity structure-activity relationship for alkyl sulfates

✍ Scribed by Dyer, S. D. ;Lauth, J. R. ;Morrall, S. W. ;Herzog, R. R. ;Cherry, D. S.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 105 KB
• Volume: 12
• Category: Article
• ISSN: 1053-4725
• DOI: 10.1002/(sici)1098-2256(1997)12:4<295::aid-tox3>3.0.co;2-3

✦ Synopsis

Much of the historical data regarding the toxicity of alkyl sulfate AS surfactants to aquatic organisms have been compromised due to excessive loss of the parent material via biodegradation and precipitation-processes especially important during chronic tests. To minimize these issues, a novel flow-through system for Ceriodaphnia dubia was developed and acute and chronic toxicity data were obtained for several AS structures. Acute toxicity increased linearly with increased alkyl chain length ( ) CL from C12AS to C16AS. However, a parabolic response was observed for reproduction where toxicity increased with alkyl chainlength from C12AS to C14AS, but decreased with increased chain length from C14AS to C18AS. Soluble vs precipitated forms of AS contribute to the parabolic relationship. A quadratic approach using the chronic end points no observed effect concentration, lowest observed effect concentration, maximum acceptable toxicant concentration, EC , and EC yielded the 50 20 20 risk assessment.