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Development of a chemically defined medium for the production of the antibiotic platensimycin by Streptomyces platensis

✍ Scribed by Falzone, Maria; Martens, Evan; Tynan, Heather; Maggio, Christian; Golden, Samantha; Nayda, Vasyl; Crespo, Emmanuel; Inamine, Gregory; Gelber, Michael; Lemence, Ryan; Chiappini, Nicholas; Friedman, Emily; Shen, Ben; Gullo, Vincent; Demain, Arnold L.

Book ID
121431486
Publisher
Springer
Year
2013
Tongue
English
Weight
168 KB
Volume
97
Category
Article
ISSN
1432-0614

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## Abstract A systematic approach was developed to identify and optimize the essential amino acids in defined minimal medium for the production of recombinant human interleukin 3 (rHuIL‐3) by __Streptomyces lividans__. Starvation trials were carried out initially to narrow down the number of probab