Development of a capillary electrophoretic method for the separation of diastereoisomers of a new human immunodeficiency virus protease inhibitor
✍ Scribed by Stefanie Leonard; Ann Van Schepdael; Tímea Iványi; István Lázár; Jan Rosier; Marc Vanstockem; Hans Vermeersch; Jos Hoogmartens
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 212 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0173-0835
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Aziridine derivatives are attracting pharmacological interest as protease inhibitors. Due to their two centers of chirality, the aziridines studied here are mixtures of two diastereomers and corresponding enantiomers. Applying cyclodextrin-modified capillary electrophoresis resulted in a baseline se
Serology has been a fundamental tool to prevent post-transfusional infection with human immunodeficiency virus (HIV) and for epidemiological surveys, the first step to attempt control of the pandemia. Enzyme immunoassay is in widespread use. Nevertheless, simpler methods are needed in many countries