## Abstract The aim of the development of composite materials is to combine the most desired properties of two or more materials. In this work, the biodegradable character, good controlled‐release properties, and natural origin of starch‐based biomaterials are combined with the bioactive and bone‐b
Development of a bioactive glass fiber reinforced starch–polycaprolactone composite
✍ Scribed by H. Jukola; L. Nikkola; M. E. Gomes; F. Chiellini; M. Tukiainen; M. Kellomäki; E. Chiellini; R. L. Reis; N. Ashammakhi
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 147 KB
- Volume
- 87B
- Category
- Article
- ISSN
- 1552-4973
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✦ Synopsis
Abstract
For bone regeneration and repair, combinations of different materials are often needed. Biodegradable polymers are often combined with osteoconductive materials, such as bioactive glass (BaG), which can also improve the mechanical properties of the composite. The aim of this work was to develop and characterize BaG fiber reinforced starch–poly‐ε‐caprolactone (SPCL) composite. Sheets of SPCL (30/70 wt %) were produced using single‐screw extrusion. They were then cut and compression‐molded in layers with BaG fibers to form composite structures with different combinations. Mechanical and degradation properties of the composites were studied. The actual amount of BaG in the composites was determined using combustion tests. Initial mechanical properties of the reinforced composites were at least 50% better than the properties of the nonreinforced specimens. However, the mechanical properties of the composites after 2 weeks of hydrolysis were comparable to those of the nonreinforced samples. During the 6 weeks hydrolysis the mass of the composites had decreased only by about 5%. The amount of glass in the composites remained as initial for the 6‐week period of hydrolysis. In conclusion, it is possible to enhance initial mechanical properties of SPCL by reinforcing it with BaG fibers. However, mechanical properties of the composites are typical for bone fillers and strength properties need to be further improved for allowing more demanding bone applications. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2008
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