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Development andin Vitro-in VivoEvaluation of a Multiparticulate Sustained Release Formulation of Diltiazem

✍ Scribed by Shun Por Li; Robert G. Felt; Louis C. Di Paolo; Mei-Ying Huang; Robert O. Williams III

Book ID
110346488
Publisher
Springer US
Year
1995
Tongue
English
Weight
912 KB
Volume
12
Category
Article
ISSN
0724-8741

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✍ Kazuo Murata; Kazuo Noda πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 379 KB πŸ‘ 1 views

The in vivo performance of multiparticulate sustained-release diltiazem preparations [HER-SR(A,B,C)] coated with water-insoluble polymer (ethylcellulose), to control the in vitro dissolution rate, was evaluated in dogs. With a decrease in dissolution rate, HER-SR maintained sustained-release charact