Development and validation of bioanalytical methods for imidafenacin (KRP-197/ONO-8025) and its metabolites in human urine by using liquid chromatography-tandem mass spectrometry
✍ Scribed by Yuichi Masuda; Norihiro Kanayama; Shigeru Manita; Satoshi Ohmori; Tsuyoshi Ooie
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 257 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.837
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
An SPE-LC-MS/MS method was developed, validated and applied to the determination of nicotine and five major metabolites in human urine: cotinine, trans-3'-hydroxycotinine, nicotine-N-glucuronide, cotinine-N-glucuronide and trans-3'-hydroxycotinine-O-glucuronide. A 500 microL urine sample was pH-adju
## Abstract A rapid, simple and specific method for estimation of anastrazole in human plasma was validated using letrozole as internal standard. The analyte and internal standard were extracted from plasma using simple solid‐phase extraction. The compound were separated on a reverse‐phase column w