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Development and validation of an HPLC method for simultaneous determination of trimethoprim and sulfamethoxazole in human plasma

✍ Scribed by Esin Sayar; Selma Sahin; Semsettin Cevheroglu; A. Atilla Hıncal


Book ID
107697955
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
243 KB
Volume
35
Category
Article
ISSN
0378-7966

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✍ Daisuke Teshima; Kaori Otsubo; Kazutaka Makino; Yoshinori Itoh; Ryozo Oishi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB 👁 2 views

## Abstract A capillary electrophoretic method for the simultaneous determination of sulfamethoxazole and trimethoprim in plasma was developed. Sulfamethoxazole and trimethoprim extracted from human plasma with ethyl acetate were analyzed at 20 kV and 25°C using 15 mm phosphate buffer (pH 6.2) as t