Development and validation of a robust capillary electrophoresis method for impurity profiling of calcium levofolinate including the (6R,2'S)-diastereomer using statistical experimental design

Development and validation of a robust c

Development and validation of a robust capillary electrophoresis method for impurity profiling of etomidate including the determination of chiral purity using a dual cyclodextrin system

✍ Manuela Hammitzsch; Ramisetti N. Rao; Gerhard K. E. Scriba 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB 👁 1 views

## Abstract An enantioselective CE assay for the simultaneous determination of the enantiomeric purity and of related substances of etomidate has been developed and validated using a binary chiral selector system employing 30 mg/mL β‐CD and 4.6 mg/mL sulfated‐β‐CD in a 150 mM potassium phosphate bu