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Development and validation of a mass spectrometric detection method of peginesatide in dried blood spots for sports drug testing

✍ Scribed by Möller, Ines; Thomas, Andreas; Geyer, Hans; Schänzer, Wilhelm; Thevis, Mario

Book ID: 111902201
Publisher: Springer
Year: 2012
Tongue: English
Weight: 349 KB
Volume: 403
Category: Article
ISSN: 1618-2650
DOI: 10.1007/s00216-012-6043-2

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## Abstract Sildenafil (SDL) is a phosphodiesterase type 5 inhibitor and it is approved for the treatment of erectile dysfunction and pulmonary hypertension. SDL is extensively metabolized to its pharmacologically active metabolite, desmethyl‐sildenafil (DSDL). A sensitive and specific GC/MS method