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Development and validation of a chromatographic method for determining Clematichinenoside AR and related impurities

✍ Scribed by Yang Zhou, Yue Guan, Ji Shi, Xiaolin Zhang, Lan Yao, Lifang Liu


Book ID
119912113
Publisher
Chemistry Central
Year
2012
Tongue
English
Weight
359 KB
Volume
6
Category
Article
ISSN
1752-153X

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## Abstract A novel stability‐indicating high‐performance liquid chromatographic (HPLC) method was developed and validated for assay and determination of impurities of emtricitabine in drug substance. Emtricitabine was found to be degraded under acidic, alkaline, and oxidative stress conditions and