✦ LIBER ✦

Development and Scale up of Preparative HIC for the Purification of a Recombinant Therapeutic Protein

✍ Scribed by K. Graumann; A. A. Ebenbichler

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 319 KB
Volume: 28
Category: Article
ISSN: 0930-7516
DOI: 10.1002/ceat.200500165

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Antibody variable region interactions wi

Antibody variable region interactions with Protein A: Implications for the development of generic purification processes

✍ Sanchayita Ghose; Martin Allen; Brian Hubbard; Clayton Brooks; Steven M Cramer 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB 👁 1 views

## Abstract In this paper, a wide range of antibodies from various subclasses and subfamilies are employed to evaluate the creation of generic separation processes using Protein A chromatography. The reasons for elution pH differences amongst several IgG1s, IgG2s, antibody fragments, and Fc‐fusion

Combined approach of NMR and chemometric

Combined approach of NMR and chemometrics for screening peptones used in the cell culture medium for the production of a recombinant therapeutic protein

✍ Ying Luo; Guoxiang Chen 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB 👁 1 views

## Abstract Soy peptones or soy hydrolysates are widely used as key medium additives in serum‐free cell culture processes for industrial production of therapeutic recombinant proteins. The heterogeneous nature of these vegetable‐derived materials can lead to substantial lot‐ to‐lot variability in c

Microscale to manufacturing scale-up of

Microscale to manufacturing scale-up of cell-free cytokine production—a new approach for shortening protein production development timelines

✍ James F. Zawada; Gang Yin; Alexander R. Steiner; Junhao Yang; Alpana Naresh; Sus 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 431 KB 👁 1 views

ChemInform Abstract: Development and Pil

ChemInform Abstract: Development and Pilot-Scale Demonstration of a Process for Inhibitors of the HIV Nucleocapsid Protein, NCp7.

✍ P. J. FIORE; T. P. PULS; J. C. WALKER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Expanded bed adsorption as a primary rec

Expanded bed adsorption as a primary recovery step for the isolation of the insulin precursor MI3 process development and scale up

✍ Peter Brixius; Inger Mollerup; Ole Elvang Jensen; Markus Halfar; Jörg Thömmes; M 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB 👁 2 views