A simple and rapid method for the determination of (S)-mephenytoin 4-hydroxylase activity by human liver microsomal cytochrome P-450 has been developed. [Methyl-'4C]mephenytoin was synthesized by alkylation of Snirvanol with 14CHJ and used as a substrate. AAer incubation of [mefhy/-'4C]mephenytoin w
โฆ LIBER โฆ
Development and preliminary application of a simple assay of S-mephenytoin 4-hydroxylase activity in human liver microsomes
โ Scribed by K. Chiba; K. Manabe; K. Kobayashi; Y. Takayama; M. Tani; T. Ishizaki
- Book ID
- 105575855
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 474 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0031-6970
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