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Development and in vivo testing of a Nitinol tracheal stent

✍ Scribed by Samanta B. Vearick; Marcelo D. O. Michelon; Lirio Schaeffer; Rogério G. Xavier; Gabriel Kuhl; Paulo R. S. Sanches; Marcos E. S. Duarte

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
366 KB
Volume
83B
Category
Article
ISSN
1552-4973

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✦ Synopsis

Abstract

This article describes the development of a Nitinol tracheal stent (HCPA NiTi‐stent) and its application in a feline animal model. Straight‐annealed, bright‐polished Nitinol wire (55.8%Ni‐44.2%Ti) was weaved around a 40‐mm‐long metal fixture with 8‐mm diameter. The prototypes were submitted to different times of shape‐setting heat treatment (530°C), which resulted in stents of different colors and caused some variation in length and diameter. The prototypes were then submitted to compression testing, and the most resistant pieces, requiring the greatest force to achieve a 25% reduction in diameter and presenting the least variation in length and diameter (dark blue, 9 min of heat treatment), were submitted to fatigue testing. After that, only dark blue stents were manufactured and implanted in felines. No migration, tracheal stenosis, or any other type of damage were observed after 40 weeks. The integrity of the tracheal wall in contact with the stent was confirmed by macro and microscopic analyses. The development and in vivo testing of the HCPA NiTi‐stent were successful. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2007

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