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Development and in vitro evaluation of thiolated chitosan—Poly(methacrylic acid) nanoparticles as a local mucoadhesive delivery system

✍ Scribed by Mohammad Reza Saboktakin; Roya M. Tabatabaie; Abel Maharramov; Mohammad Ali Ramazanov

Book ID
116542418
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
432 KB
Volume
48
Category
Article
ISSN
0141-8130

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The purpose of the present study was to design and evaluate a novel vaginal delivery system for nystatin based on mucoadhesive polymers. L-Cysteine and cysteamine, respectively, were covalently attached to poly(acrylic acid), and the two different thiolated polymers were evaluated in vitro regarding