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Development and improvement of a serum-free suspension process for the production of recombinant adenoviral vectors using HEK293 cells

✍ Scribed by Yung-Shyeng Tsao; Russell Condon; Eugene Schaefer; Peggy Lio; Zhong Liu


Book ID
110396873
Publisher
Springer
Year
2001
Tongue
English
Weight
304 KB
Volume
37
Category
Article
ISSN
0920-9069

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## Abstract ## Background One of the major limitations to the use of adeno‐associated virus (AAV) vectors for gene therapy has been the difficulty in producing enough vector to supply a clinical trial. More than 20 000 roller bottles may be required to generate AAV by the traditional transient tra