Development and homeostasis of dendritic cells

✍ Scribed by Kang Liu; Michel C. Nussenzweig

• Book ID: 102163571
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 185 KB
• Volume: 40
• Category: Article
• ISSN: 0014-2980
• DOI: 10.1002/eji.201040501

✦ Synopsis

Abstract

DC are specialized antigen‐presenting cells that serve as essential mediators of immunity and tolerance. DC's functional versatility is enabled in part by the various DC subsets with heterogeneous cell surface markers and anatomic locations. Here, we review the development and homeostasis of DC found in lymphoid and nonlymphoid tissues.