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Development and evaluation of paclitaxel loaded PLGA:poloxamer blend nanoparticles for cancer chemotherapy

โœ Scribed by Gupta, Prem N.; Jain, Sharad; Nehate, Chetan; Alam, Noor; Khare, Vaibhav; Dubey, Ravindra Dhar; Saneja, Ankit; Kour, Smit; Singh, Shashank K.

Book ID
124117426
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
905 KB
Volume
69
Category
Article
ISSN
0141-8130

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A novel paclitaxel-loaded poly(ฮต-caprola
A novel paclitaxel-loaded poly(ฮต-caprolactone)/Poloxamer 188 blend nanoparticle overcoming multidrug resistance for cancer treatment
โœ Yangqing Zhang; Lina Tang; Leilei Sun; Junbo Bao; Cunxian Song; Laiqiang Huang; ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 562 KB

Multidrug resistance (MDR) of tumor cells is a major obstacle to the success of cancer chemotherapy. Poloxamers have been used in cancer therapy to overcome MDR. The objective of this research is to test the feasibility of paclitaxel-loaded poly(epsilon-caprolactone)/Poloxamer 188 (PCL/Poloxamer 188