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Development and evaluation of diclofenac sodium thermorevesible subcutaneous drug delivery system

✍ Scribed by Fazli Nasir; Zafar Iqbal; Jamshaid A. Khan; Abad Khan; Fazli Khuda; Lateef Ahmad; Amirzada Khan; Abbas Khan; Abdullah Dayoo; Roohullah


Book ID
118454367
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
677 KB
Volume
439
Category
Article
ISSN
0378-5173

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The aim of the present study was to investigate the effect of poly(acrylic acid)-cysteine (PAA-cysteine) exhibiting a molecular mass of 100 and 250 kDa and reduced glutathione (GSH) on the absorption of the P-glycoprotein (P-gp) and cytochrome P450 (CYP450) substrate paclitaxel in vitro and in vivo.