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Development and evaluation of BioScore : A biomarker panel to enhance prognostic algorithms for clear cell renal cell carcinoma

โœ Scribed by Alexander S. Parker; Bradley C. Leibovich; Christine M. Lohse; Yuri Sheinin; Susan M. Kuntz; Jeanette E. Eckel-Passow; Michael L. Blute; Eugene D. Kwon


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
208 KB
Volume
115
Category
Article
ISSN
0008-543X

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Multiple renal cell tumours from three unrelated patients have been analysed for loss of heterozygosity of 3p, mutation of VHL, and chromosome 7 and 17 imbalances. Loss of 3p alleles is characteristic for clear cell type tumours and the combination of 17, 117 for chromophilic cell type tumours. Thus