𝔖 Bobbio Scriptorium
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Development and Evaluation of an in Silico Model for hERG Binding

✍ Scribed by Song, Minghu; Clark, Matthew


Book ID
118065938
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
183 KB
Volume
46
Category
Article
ISSN
0095-2338

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πŸ“œ SIMILAR VOLUMES


Prospective Validation of a Comprehensiv
✍ Munikumarβ€…R. Doddareddy; Elisabethβ€…C. Klaasse; Shagufta; Adriaanβ€…P. IJzerman; An πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 666 KB

Ligand-based in silico hERG models were generated for 2 644 compounds using linear discriminant analysis (LDA) and support vector machines (SVM). As a result, the dataset used for the model generation is the largest publicly available (see Supporting Information). Extended connectivity fingerprints