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Development and Characterization of a Rabbit Corneal Endothelial Cell Line

✍ Scribed by Jun Seop Shin; In Keun Jang; Chan Wha Kim; Jae Chan Kim

Book ID
106327051
Publisher
Springer
Year
2004
Tongue
English
Weight
248 KB
Volume
48
Category
Article
ISSN
0021-5155

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The purpose of this study is to assess the permeability of acyclovir (ACV) prodrugs through the rabbit corneal cell line (SIRC) as well as the cornea, and characterize the SIRC cell line for transport and metabolism studies of ester prodrugs. Prodrug derivatization of an acycloguanosine antiviral ag