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Development and Application of an Automated Solution Stability Assay for Drug Discovery

โœ Scribed by Di, Li ;Kerns, Edward H. ;Chen, Hong ;Petusky, Susan L.

Book ID
119974053
Publisher
SAGE Publications
Year
2006
Tongue
English
Weight
245 KB
Volume
11
Category
Article
ISSN
2472-5552

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A medium-throughput, compound-saving, thermodynamic solubility assay for early drug development was developed. Solid compound suspended in heptane was used for simple, time-saving, and flexible compound distribution into 96-well plates, with minor risk to generate new physical forms during dispensin