Computer-integrated manufacturing requires models of manufacturing processes to be implemented on the computer. Process models are required for designing adaptive control systems and selecting optimal parameters during process planning. Mechanistic models developed from the principles of machining science are useful for implementing on a computer. However, in spite of the progress being made in mechanistic process modeling, accurate models are not yet available for many manufacturing processes. Empirical models derived from experimental data still play a major role in manufacturing process modeling. Generally, statistical regression techniques are used for developing such models. However, these techniques suffer from several disadvantages. The structure (the significant terms) of the regression model needs to be decided a priori. These techniques cannot be used for incrementally improving models as new data becomes available. This limitation is particularly crucial in light of the advances in sensor technology that allow economical on-line collection of manufacturing data. In this paper, we explore the use of artificial neural networks (ANN) for developing empirical models from experimental data for a machining process. These models are compared with polynomial regression models to assess the applicability of ANN as a model-building tool for computer-integrated manufacturing.