Deuterium-Hydrogen Exchange of Muscle Proteins *
β Scribed by Hartshorne, D. J.; Stracher, A.
- Book ID
- 126296722
- Publisher
- American Chemical Society
- Year
- 1965
- Tongue
- English
- Weight
- 598 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0006-2960
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π SIMILAR VOLUMES
Hydrogen-deuterium exchange can be a sensitive indicator of protein structural integrity. Comparisons were made between cerebroside sulfate activator protein (CSAct) in the native state and after treatment with guanidine hydrochloride plus dithiothreitol. Native protein has three internal disulfide
## Abstract Dimethylpyridines undergo deuteriumβhydrogen exchange when heated in deuterium oxide containing potassium carbonate at ring positions 2 and 6 when these positions are unsubstituted and at methyl groups located at ring positions 2,4, and 6 exclusively.