Deuterium and tritium labeling of (3-xenyl)cyclohexane by Clemmensen and Wolff-Kishner reduction

Preparation of tritium-labeled compounds

Preparation of tritium-labeled compounds. VI. Nafoxidine hydrochloride by clemmensen reduction and by solvent exchange of intermediates

✍ Richard C. Thomas; Daniel Lednicer 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 268 KB

## Abstract Tritium‐labeled nafoxidine hydrochloride, 1‐{__p__‐[2‐(N‐pyrro‐lidino) ethoxy]phenyl}‐3,4‐dihydro‐6‐methoxy‐2‐phenylnaphthalene hydrochloride (I), having two different intramolecular distributions of tritium, was prepared from 6‐methoxy‐2‐phenyl‐1‐tetralone (IV). I was labeled in the 4