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Deuterated analogs of verapamil and nifedipine. Synthesis and biological activity

✍ Scribed by D Rampe; PW Hake; B Børretzen; KH Holm; L Skattebøl

Book ID
118406683
Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
499 KB
Volume
28
Category
Article
ISSN
0223-5234

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Synthesis of deuterated optically active
Synthesis of deuterated optically active verapamil and gallopamil, and of N-13C-methyl-verapamil
✍ Louis J. Theodore; Wendel L. Nelson 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 624 KB

Deuterated (-)-verapamil, (28)-(-)-2-(2,5,6-€I3-3,4-dimethoxyphenyl)-2-2 2 isopropyl-5-[(2,5,6-H 3,4-dimethoxyphenethyl)methylamino]valeronitrile, and its analog (-)-H gallopamil. (2S)-(-)-2-(2,6-H2-3,4,5-trimethoxyphenyl)-2isopropyl-5-[ (2,s ,6-H3-3 ,4-dimethoxyphenethyl)methylamino]valeronitrile,