Detrimental effect of nitric oxide inhibition in experimental bacterial meningitis

Increase in experimental pulmonary metas

Increase in experimental pulmonary metastasis in mice by L-arginine under inhibition of nitric oxide production by NG-nitro-L-arginine methyl ester

✍ Takashi Yamamoto; Nobuyuki Terada; Akitoshi Seiyama; Yasuko Nishizawa; Hitoshi A 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 59 KB

As we have previously reported, intraperitoneal injections of NG-nitro-L-arginine methyl ester [L-NAME; a competitive inhibitor of nitric oxide (NO) synthase] before and after the injection of B16 melanoma cells through a tail vein increased experimental pulmonary metastasis, while simultaneous inje