Detoxification of endotoxin by aluminum hydroxide adjuvant
โ Scribed by Yi Shi; Harm HogenEsch; Fred E. Regnier; Stanley L. Hem
- Book ID
- 117430140
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 83 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0264-410X
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Aluminum-salt adjuvants are widely used to increase immunogenicity of recombinant protein vaccines. However, when vaccines formulated with these adjuvants are frozen or lyophilized, losses of efficacy are often reported. This loss of potency is usually attributed to the aggregation of adjuvant parti