The Phenylacetyl Group—The First Amino P
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Prof. Dr. Herbert Waldmann; Dr. Armin Reidel
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Article
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1997
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John Wiley and Sons
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English
⚖ 436 KB
Penicillin G acylase from __E. coli__ was used to cleave the phenylacetyl group—the first enzyme‐labile protecting group for the amino function of nucleobases. Now protected oligonucleotides can be unmasked both in solution and on solid supports with this versatile enyzme under mild conditions (pH 7