Determining urinary trace elements (Cu, Zn, Pb, As, and Se) in patients with bladder cancer
✍ Scribed by Chang-Ni Lin; Lai-Hao Wang; Kun-Hung Shen
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 101 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0887-8013
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✦ Synopsis
Objectives: Trace elements are essential components of biological structures, but they can be toxic at concentrations beyond those necessary for their biological functions. Methods: A study group of 30 patients with bladder cancer and a control group of 30 healthy volunteers were measured for trace elements using a graphite furnace atomic absorption spectrophotometer. Results: Urinary zinc and selenium levels in patients were significantly (Po0.05) higher than those in controls, but urinary copper, arsenic, and lead were not significantly different.
Conclusion:
This case-control study suggests that zinc and selenium concentrations are associated with the proliferation of bladder cancer cells because zinc and selenium are excreted in the urine of bladder cancer patients.