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Determining the role of the centrosome in establishing epithelial cell polarity

✍ Scribed by Jessica Feldman; James Priess

Book ID
118505531
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
40 KB
Volume
356
Category
Article
ISSN
0012-1606

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Cultured human erythroleukemia (HEL) cells were used to study the genesis of polarity in single cells. HEL cells grow in suspension in culture medium, but attach and spread on fibronectin when treated with 10 nM phorbol myristate acetate. If the spread cells are treated with dibutyryl cyclic adenosi