Drug–Cyclodextrin Association Constants
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Angelina Angelova; Catherine Ringard-Lefebvre; Adam Baszkin
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Article
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1999
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Elsevier Science
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English
⚖ 138 KB
The compression of water-insoluble drug monolayers spread on the aqueous subphase containing cyclodextrins (CD) led to a shift of surface pressure (pi)-area (A) isotherms toward smaller molecular areas with respect to the pi-A isotherms on the pure water subphase. The displacement of the compression