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Determining Elasticities from Multiple Measurements of Flux Rates and Metabolite Concentrations : Application of the Multiple Modulation Method to a Reconstituted Pathway

โœ Scribed by Christoph Giersch


Book ID
115131653
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
924 KB
Volume
227
Category
Article
ISSN
1432-1327

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Determining Elasticities from Multiple M
โœ Christoph Giersch ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 528 KB

A method to determine elasticities of individual enzymes within a metabolic pathway is developed. The method is based on measurements of steady-state metabolite pools and flux rates rather than the usual kinetic in vitro measurements on isolated enzymes. In this respect, it is an extension of the "d