A liquid chromatographyic/turbo ionspray tandem mass spectrometric (LC/MS/MS) method was developed and validated for the determination of L-753,037, a potent endothelin receptor antagonist currently under development for the treatment of cardiovascular diseases, in human plasma. L-753,037 is extract
Determination of xanomeline in human plasma by ionspray tandem mass spectrometry
โ Scribed by A. T. Murphy; P. L. Bonate; S. C. Kasper; T. A. Gillespie; A. F. DeLong
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 381 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1076-5174
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A liquid chromatographic/tandem mass spectrometric (LC/MS/MS) assay was developed for the quantitative determination of olanzapine (LY170053, OLZ) in human plasma and serum. Bond Elut solid-phase extraction C 2 cartridges (single cartridge or 96-well format), in conjunction with a positive pressure
Rapid, sensitive and selective methods were developed for the determination of dextromethorphan and its major metabolite, dextrorphan, in human plasma using liquid chromatography/tandem mass spectrometry (LC/MS/MS). Plasma samples spiked with stable-isotope internal standards were prepared for analy
## Abstract A sensitive and speci๏ฌc procedure for simultaneous quantitation of chlorpheniramine and pseudoephedrine in human plasma has been developed and validated. Analytes were extracted from plasma samples by liquidโliquid extraction, separated on a Diamonsil C~18~ column (250 ร 4.6 mm i.d.) an
## Abstract A method has been developed for the simultaneous quantification of metformin (I) and glipizide (II) in human plasma. It is based on highโperformance liquid chromatography with electrospray ionization tandem mass (LCโESIโMS/MS) spectrometric detection in positive ionization mode. Phenfor