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Determination of von Willebrand factor activity with collagen-binding assay and diagnosis of von Willebrand disease: Effect of collagen source and coating conditions

✍ Scribed by Ryszard Paczuski


Book ID
114486562
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
83 KB
Volume
140
Category
Article
ISSN
1532-6543

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Von Willebrand factor (vWf) functions both as a carrier of factor VIII (fVIII) in plasma and as an adhesive protein providing the primary link between collagen of the extracellular matrix and platelets sequestered from blood flow. The functional activity of vWf correlates with the level of its bindi